Author Topic: High cholesterol and atherosclerotic plaque  (Read 7471 times)

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Offline Alan

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Re: High cholesterol and atherosclerotic plaque
« Reply #45 on: 07 April 2016, 05:37:40 AM »
Nick

I am glad to hear that Eli Lilly et al have seen the light.  May I ask if these are the PCSK9 drugs they have been touting?  I was asked to participate in a study about these locally and I said "only if I can be assured that I will get the placebo".

I doubt it; this was on last night's news: http://www.9news.com.au/health/2016/04/07/13/24/powerful-new-cholesterol-drug-approved-for-use-in-australia
Cheers, Alan, T2, Australia.
--
Everything in Moderation - Except Laughter.
There is nothing I could eat I like more than my eyes.
Type 2 Diabetes - A Personal Journey (latest: Small New York Baked Low Carb Cheesecake)
Born Under a Wandering Star (Latest:Dambulla, Sigiriya and Polonuwarra, Sri Lanka)

Offline Pattidevans

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Re: High cholesterol and atherosclerotic plaque
« Reply #46 on: 07 April 2016, 09:28:49 AM »
Evidently they are not the same drug and the two drugs work in different ways, but if you check my 2nd paragraph you'll note that I said that although they have dropped that particular drug, it's more about seeing that raised HDL doesn't help rather than debunking the lipid hypotheses.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline lozzark

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Re: High cholesterol and atherosclerotic plaque
« Reply #47 on: 01 May 2016, 02:33:59 AM »
Evidently they are not the same drug and the two drugs work in different ways, but if you check my 2nd paragraph you'll note that I said that although they have dropped that particular drug, it's more about seeing that raised HDL doesn't help rather than debunking the lipid hypotheses.
I think the point about the lipid hypothesis is that the trials reduced LDL by some considerable margin, but the drug recipients did not reduce their atherosclerosis or incidence of heat attack.

I now have over 40 causes of heart disease, but some need explaining.  I'll post them when I have more time.
T2 Dx 2000 Metformin Gliclazide HbA1c 53 BP 129/79 Cholesterol 5.4, HDL 1.16, LDL 2.9.

Offline Pattidevans

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Re: High cholesterol and atherosclerotic plaque
« Reply #48 on: 01 May 2016, 12:09:49 PM »
Right, thanks Nick that will be good.  Incidentally have you read Malcolm Kendrick's series of blogs (I think it's 12 so far) in the causes of heart disease.  Most interesting.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline lozzark

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Re: High cholesterol and atherosclerotic plaque
« Reply #49 on: 01 May 2016, 09:17:45 PM »
Right, thanks Nick that will be good.  Incidentally have you read Malcolm Kendrick's series of blogs (I think it's 12 so far) in the causes of heart disease.  Most interesting.
I've read some but not al.  In the Great Cholesterol con, he thinks stress is a big factor.  I'm sure it is, there are still many more.  I'm still working on the list.
T2 Dx 2000 Metformin Gliclazide HbA1c 53 BP 129/79 Cholesterol 5.4, HDL 1.16, LDL 2.9.

Offline Dr DeEath

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Re: High cholesterol and atherosclerotic plaque
« Reply #50 on: 12 October 2017, 01:40:24 PM »
Someone I met at the cardio clinic has passed me on some information which may be a pointer to why I have PAD and CVD despite never having had a cholesterol level above 4.2. Once I have digested it and made sure it is not quackery I will add it to this thread.
T1 for over 50 years.  MDI on Porcine insulin.  Lisinopril and Atorvastatin.

Offline Pattidevans

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Re: High cholesterol and atherosclerotic plaque
« Reply #51 on: 12 October 2017, 05:30:46 PM »
Thanks.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline sedge

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Re: High cholesterol and atherosclerotic plaque
« Reply #52 on: 12 October 2017, 10:04:37 PM »
Sounds interesting Dr D !
Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4