Author Topic: Prednisalone and Insultard query  (Read 254 times)

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Offline pms543

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Prednisalone and Insultard query
« on: 16 October 2017, 06:39:26 AM »

Long story short: Been o n Prednisalone for over 16months now,  reduced currently to 17mg a day and as the eye hosp think its caused eye probs for me, they added in 150mg Azaithiaprine 4 months back with the view to completely come off pred.
I am currently on 44 units Insultard


My query is, in the past few months ( cant pin date ) my sleep has been awful to the point am now almost a total insomniac.
Rheumatologist didn't agree the pred is the culprit but my online research suggests otherwise.


I am waiting to discuss with my DN this week but wondered if anyone had experience?


I decided to try taking pred at 8pm not 8am and obv take my insultard at same time. 1st night no difference and last night slept a bit more BUT was up to loo 4 x in 4 hours..


Any ideas? thanks
Poppet x

I have Coeliac disease.

Diagnosed Type 2 16/08/2010

OCT 2013 2 X 500g Glucosaphage

Current slow release Metformin 2000g

Victoza 1.2 daily

36 Units Insultard

30mg Prednisalone

2 x 500mg Calcichew D3 Forte

30mg Amitriptyline


16/11/2010 1st HbA1c 8.5, HDL 1.1, LDL 2.7, Trigs 1.6 
17/02/2015 HbA1c 108mmol, HDL 1.5, LDL 4.3, Trigs 2.7 Total Chol 4.7

25/04/2017 HbA1c  84mmol,Chol 7.7

Offline sedge

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Re: Prednisalone and Insultard query
« Reply #1 on: 16 October 2017, 03:25:25 PM »
I doubt very much indeed whether it's anything whatsoever to do with the insulin - a lady member (Pumper Sue who posts in the main on another forum hence we hardly see her these days) also has Addison's so she's permanently on pred as well as Insulin but was T1 well before before the A's and I've not heard her say anything - but obviously do ask.  The main thing any steroid does is increase a person's BG and you just have to increase the doseage to cater for that.

Do you test your BG when this occurs and if so what is it - high low or OK?  What I mean is - is the dose of insulin currently correct?

And, sorry Poppet, it isn't at all obvious when you take your Insulatard - how could it be?  I'm wondering if the sleeplessness is more to do with your BG during the night than the pred but as I've never been on any steroid obviously I don't know.

Re loo visits - regrettably I have to say though 4 times in 4 hours is a bit too much, that happens to me occasionally - but I know those nights when I go it's not as much as normal, so conclude for whatever reasons my bladder isn't fully emptying.
Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4

Offline Pattidevans

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Re: Prednisalone and Insultard query
« Reply #2 on: 16 October 2017, 03:35:02 PM »
Sedge


I think PMs was asking if it was Prednisalone that was causing the insomnia no the Insulatard.


Pms543


I have to say a very quick google took me to the NHS’s own website https://beta.nhs.uk/medicines/prednisolone/
Where it clearly states that a common side effect is “not able to sleep”,so I suggest you print that out and show it to your Rheumatokogist.


Re: going to the loo a lot, as you know high BGs will do that to you.  When you take your Insulatard it will be at it’s lowest strength until it ramps up a bit after injection, usually an hour or an hour and a half before it will be full strength, during that time your Prednisalone will likely be at it’s full strength so you have a double whammy pushing BGs up.  Next time TEST!  Your meter is the tool to unravel this mystery :)


Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline pms543

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Re: Prednisalone and Insultard query
« Reply #3 on: 16 October 2017, 07:40:35 PM »
Do you test your BG when this occurs and if so what is it - high low or OK?  What I mean is - is the dose of insulin currently correct? ALMOST BUT HAVE BEEN HAPHAZARD DUE TO CIRCUMSTANCES RECENTLY. NOT BEEN ABLE TO TAKE THEM REGULARLY BUT I DONT THINK THIS IS THE LACK OF SLEEP ISSUE

And, sorry Poppet, it isn't at all obvious when you take your Insulatard - how could it be?  I'm wondering if the sleeplessness is more to do with your BG during the night than the pred but as I've never been on any steroid obviously I don't know. WRONG USE OF WORDS AS WAS WRITTEN SLEEP DEPRIVED. MEANT I TAKE MY INSULTARD AT SAME TIME AS PREDS. PERIOD.

Re loo visits - regrettably I have to say though 4 times in 4 hours is a bit too much, that happens to me occasionally - but I know those nights when I go it's not as much as normal, so conclude for whatever reasons my bladder isn't fully emptying.  NOPE PROPER EMTYING OF BLADDER AND MY BGS NOT NECC HIGH

THANKS SEDGE
Poppet x

I have Coeliac disease.

Diagnosed Type 2 16/08/2010

OCT 2013 2 X 500g Glucosaphage

Current slow release Metformin 2000g

Victoza 1.2 daily

36 Units Insultard

30mg Prednisalone

2 x 500mg Calcichew D3 Forte

30mg Amitriptyline


16/11/2010 1st HbA1c 8.5, HDL 1.1, LDL 2.7, Trigs 1.6 
17/02/2015 HbA1c 108mmol, HDL 1.5, LDL 4.3, Trigs 2.7 Total Chol 4.7

25/04/2017 HbA1c  84mmol,Chol 7.7

Offline pms543

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Re: Prednisalone and Insultard query
« Reply #4 on: 16 October 2017, 07:42:57 PM »

Sedge


I think PMs was asking if it was Prednisalone that was causing the insomnia no the Insulatard.


Pms543


I have to say a very quick google took me to the NHS’s own website https://beta.nhs.uk/medicines/prednisolone/
Where it clearly states that a common side effect is “not able to sleep”,so I suggest you print that out and show it to your Rheumatokogist.


Re: going to the loo a lot, as you know high BGs will do that to you. I AGREE
When you take your Insulatard it will be at it’s lowest strength until it ramps up a bit after injection, usually an hour or an hour and a half before it will be full strength, during that time your Prednisalone will likely be at it’s full strength so you have a double whammy pushing BGs up.  OK
Next time TEST!  Your meter is the tool to unravel this mystery :) THANKS


I never seem to ask what I really want to know......I really just wanted to know if changing my time of taking the 2 above, wouild be ok to do so?
If it is the pred inducing awakeness then it makes sense to change time I take it?







I never seem to ask what I really want to know......I really just wanted to know if changing my time of taking the 2 above, wouild be ok to do so?
If it is the pred inducing awakeness then it makes sense to change time I take it?
Poppet x

I have Coeliac disease.

Diagnosed Type 2 16/08/2010

OCT 2013 2 X 500g Glucosaphage

Current slow release Metformin 2000g

Victoza 1.2 daily

36 Units Insultard

30mg Prednisalone

2 x 500mg Calcichew D3 Forte

30mg Amitriptyline


16/11/2010 1st HbA1c 8.5, HDL 1.1, LDL 2.7, Trigs 1.6 
17/02/2015 HbA1c 108mmol, HDL 1.5, LDL 4.3, Trigs 2.7 Total Chol 4.7

25/04/2017 HbA1c  84mmol,Chol 7.7

Offline sedge

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  • Posts: 13,785
Re: Prednisalone and Insultard query
« Reply #5 on: 16 October 2017, 09:58:42 PM »
Poppet

FWIW - Sue has actually contacted me and said VERY firmly that it MUST not be taken at night!  - because it always does interfere with sleep.
Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4

Offline pms543

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  • Posts: 710
Re: Prednisalone and Insultard query
« Reply #6 on: 16 October 2017, 10:31:32 PM »

Prednisolone is renowned and listed sleep problems as a side affect, sedge


If its keeping me awake at night as I take it in morning, then would it not reverse if taken at night? who knows!
Poppet x

I have Coeliac disease.

Diagnosed Type 2 16/08/2010

OCT 2013 2 X 500g Glucosaphage

Current slow release Metformin 2000g

Victoza 1.2 daily

36 Units Insultard

30mg Prednisalone

2 x 500mg Calcichew D3 Forte

30mg Amitriptyline


16/11/2010 1st HbA1c 8.5, HDL 1.1, LDL 2.7, Trigs 1.6 
17/02/2015 HbA1c 108mmol, HDL 1.5, LDL 4.3, Trigs 2.7 Total Chol 4.7

25/04/2017 HbA1c  84mmol,Chol 7.7

Offline sedge

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  • Posts: 13,785
Re: Prednisalone and Insultard query
« Reply #7 on: 17 October 2017, 11:45:56 AM »
I understand the question but haven't a clue!  You'd need to ask someone who knows when it's at it's maximum effect - myself I'd ask a pharmacist?


Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4

Offline Pattidevans

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  • Posts: 23,650
  • It's ONLY Diabetes. It could be something worse!
Re: Prednisalone and Insultard query
« Reply #8 on: 17 October 2017, 08:13:54 PM »
Sedge has made an excellent suggestion.  Pharmacists are very knowledgeable about the drugs they dispense.  However, do you know a good one?  I'd hesitate to ask the one in the main Boots in town as it seems mostly to be locums, but the regular one in one of the smaller branches of Boots in the town is excellent.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans