Author Topic: Fiasp evaluation.  (Read 302 times)

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Offline GrammaBear

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Fiasp evaluation.
« on: 19 October 2017, 09:40:51 PM »
I receive a monthly newsletter from Gary Scheiner who wrote "Think like a Pancreas".  In this month's newsletter he wrote an article about Fiasp and I thought some of you might like to read it.

http://integrateddiabetes.com/faster-insulin-has-been-approved-now-what/?utm_source=newsletter&utm_medium=email&utm_campaign=diabetes_bites_ids_october_2017_newsletter&utm_term=2017-10-19
Type 1
Tandem Tslim pump Oct 2015
Dexcom G4 CGM Sep 2007
A1C 6.5%~ Sep 2017

Offline himtoo

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Re: Fiasp evaluation.
« Reply #1 on: 20 October 2017, 08:18:48 AM »
thank you -- I am hoping to get my consultant to change me over to it.
T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 06/2013 6.1 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014

Offline Pattidevans

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Re: Fiasp evaluation.
« Reply #2 on: 20 October 2017, 09:18:35 AM »
I was somewhat put off it by an account in another forum by someone on it who said it was fine to start with but he kept on having to increase the dose.  He included a link to a blog by another user who had found the same thing.

Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline everydayupsanddowns

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Re: Fiasp evaluation.
« Reply #3 on: 20 October 2017, 07:11:13 PM »
I used it for 3 vial’s worth. And by the end of vial 2 I knew it wasn’t for me.

Stopped working quickly (it was noticeably faster to begin with) and doses increased and worked erratically.

Switched back to NovoRapid and ‘normality’ returned immediately. NR is far from perfect but at least it’s fairly predictable - I never knew where I was with Fiasp!
Mike

Type 1 since: 1991 Last HBA1c: 45 (6.3%)  Total Chol 5.0 (1.9HDL / 2.8LDL / Trigs 0.7)
Pumping NovoRapid in a MiniMed 640G
Blogging at: www.everydayupsanddowns.co.uk

Offline Pattidevans

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Re: Fiasp evaluation.
« Reply #4 on: 20 October 2017, 07:20:31 PM »
Those were the reasons I read fir people not really liking it Mike.  I decided not to ask for it.

Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline himtoo

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Re: Fiasp evaluation.
« Reply #5 on: 20 October 2017, 11:44:36 PM »
is it totally the insulin ?? or could changes be made to pump settings to allow for it ??

just asking ??
T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 06/2013 6.1 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014

Offline Pattidevans

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Re: Fiasp evaluation.
« Reply #6 on: 21 October 2017, 10:43:32 AM »
Paul


Mike’s blog is very analytical and in detail, it might answer some of your questions.  Definitely worth a read, written well with some wry asides 😀.  Read it here ]http://www.everydayupsanddowns.co.uk/2017/08/


Apart from Mike’s curious decision to aim for 50/50 TDD at the start of the trial (sorry Mike, but it was curious,I’d have thought a direct comparison with Novo doses would have been more appropriate but you did explain your reasons) his findings run more or less parallel with the other blog I read about Fiasp.


I am using Apidra which is marginally quicker than Novorapid, though not really that much, and it is fairly predictable for me.  Though any high carb meal will see me rise quite high before coming down to a nice level hours later.. Use more to try to eliminate that spike and I will be hypo in 3 - 3.5 hours.


Last weekend we went to Bristol, mainly to visit Ikea for bits and bobs for the new house, but as a pleasant adjunct to the visit we were able to meet up with and share an evening meal with Mike.  We had traipsed around Ikea most of the day and then returning to our hotel in the City Centre we’d gone out again shopping for shoes (for Julian not for me, before those comments about women and shoes!),returning to the hotel in time for a quick cuppa and change before meeting Mike at 7pm and another smart walk to the restaurant.  We went to a tapas restaurant, so guessing carbs was a bit iffy... but when we both tested before dinner I was 3.6....obviously the exercise had dealt a little too effectively with the stodgy lunch of Swedish meat balls in gloppy over-thickened sauce as proffered by Ikea.  My pump won’t allow me to dose if under 4, so I had to wait until into the meal to do it.  For quite valid reasons which Mike will explain himself, he was a fair bit higher (9ish Mike?).   Anyway after a pleasant evening of waving our pumps at each other, discussing their ins and outs and consuming some rather tasty morsels of indeterminate carbiness, accompanied by rather nice red wine, we both tested almost identically in the 11s.  Leaving aside my later dosing, Mike had only risen by about 2mmol whereas I had shot up something like 8mmol, all too frequently the norm for me with higher carb meals.


Next morning- presumably due to the red wine and a nice Spanish brandy I was happy with my FBG of 5.5 and never went much above 6.8 all day. 
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline himtoo

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Re: Fiasp evaluation.
« Reply #7 on: 12 November 2017, 10:03:11 PM »
great blog post everyday !!!
a lot of what you experience seems to echo my experience with novorapid--  my basal bolus split is normally around 44/56 and i consume around 127 grams of carb per day.
TDD is around 49-53u per day
I also find the when high the novorapid sort of just fails to assist in bringing me back into range quickly ( very frustrating )
overall very impressive blog on fiasp !!


T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 06/2013 6.1 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014

Offline Pattidevans

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Re: Fiasp evaluation.
« Reply #8 on: 13 November 2017, 02:08:51 PM »
I am continually surprised. My IR seems to have gone on holiday... I am on only 11u of basal per 24 hrs and had pumpy on 80% all night, waking with 5.3 - so have to reduce overnight again tonight!  TDD is well under 20u.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline sedge

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Re: Fiasp evaluation.
« Reply #9 on: 13 November 2017, 05:16:00 PM »
Wish mine had Patti - perhaps we have swapped?  LOL

(though mine is mostly my knee still, not actually IR !)
Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4

Offline sedge

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Re: Fiasp evaluation.
« Reply #10 on: 13 November 2017, 05:16:34 PM »
Err - at least - I assume it's that.
Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4

Offline Pattidevans

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Re: Fiasp evaluation.
« Reply #11 on: 13 November 2017, 05:30:44 PM »
It most likely is Jen.

I think mine's the ABs.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline himtoo

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Re: Fiasp evaluation.
« Reply #12 on: 13 November 2017, 08:01:48 PM »
hey patti -- do you find IR changes with the seasons ??
I tend to need less in the winter and more in the summer ( though i know some others are the opposite to me )
T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 06/2013 6.1 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014

Offline Pattidevans

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Re: Fiasp evaluation.
« Reply #13 on: 13 November 2017, 10:31:48 PM »
I'm more like you Paul.  But as I said.. I think the Oxytetracycline is to blame for drop in insulin needs.  Apparently it increases hepatic uptake of exogenous insulin in rats according to a couple of studies... not that I am a rat you understand!
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 April 2016.


© 2015 Patti Evans

Offline himtoo

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Re: Fiasp evaluation.
« Reply #14 on: 13 November 2017, 10:46:05 PM »

no -- not a rat at all -- a queen of goodness and light in our D world !!! :)


long may you reign and preside over our forum kingdom.
T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 06/2013 6.1 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014