Author Topic: Insulin "patches" within a tablet being considered in U.S.  (Read 407 times)

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Offline himtoo

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Re: Insulin "patches" within a tablet being considered in U.S.
« Reply #1 on: 31 October 2015, 08:08:51 PM »
interesting.............. -- but one of the 10 year till fruition type treatments i suspect.
T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6) 04/18 46 (6.4)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014

Offline nytquill17

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Re: Insulin "patches" within a tablet being considered in U.S.
« Reply #2 on: 31 October 2015, 09:55:16 PM »
Hmm...I have to say, I'm not all that excited by it. By the details in the article, it looks like, same as injections, it doesn't really change what happens to the insulin once it gets into the body. You take a specific dose, it gets to your intestines and gets released all at once, works for 5 hours and is done.

Of course, that would be great news for people with a fear of needles. It may also be interesting for folks with gastroparesis, since it guarantees the insulin won't reach the bloodstream until the food does! (Although for the rest of us, that may be a negative point, if you have a sluggish digestion or are eating a large or high-fat meal!)

But by and large I really wish researchers would stop focusing on "fewer injections", because that REALLY isn't the biggest hurdle to insulin use. It only looks like it from the outside - so to me, unless researchers can point to a benefit of non-injected insulin beyond just "fewer injections," projects like this seem like the mark of people researching diabetes who don't know much about actually living with diabetes or what actual diabetics would want to improve their lives. Injected insulin works just fine, and by trying to get away from injections I'm always worried that I would also be getting away from having precision control over just how much insulin is in my body.

Now, an insulin with an adaptive action profile, THAT would be really exciting!
T1 DX 1995
Omnipod since 06/04/18 (Novorapid)
 
  ~-~-~-~
"If you can't ride, can you fall?"
"I suppose anyone can fall," said Shasta.
"I mean can you fall and get up again without crying, and mount again and fall again and yet not be afraid of falling?"
"I - I'll try," said Shasta.
  ~C.S. Lewis, The Horse and His Boy
  ~-~-~-~
"There is no answer; seek it lovingly."

Offline himtoo

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Re: Insulin "patches" within a tablet being considered in U.S.
« Reply #3 on: 31 October 2015, 10:09:12 PM »
completely agree with you nyt -- if you have to inject once a day who cares if it is 5 or 6 times a day--
I have done MDI for 18 years so the maths on total number of injections is staggering but I never bothered because of the freedom it gave me compared to mixed insulin

finding a way for "smart insulin" seems the way forward

T1 Dia Aug 1972 -pumping omnipod since 29/09/15  Losartan 100mg , simvastatin 40mg,Furosemide 40mg, Omeprazole 80mg , Doxazosin 8mg
Hba1c - 02/2014 43(6.1) 07/14 42(6.0) 08/14 40( 5.8 ) 12/14 39 (5.7) 08/15 41 ( 5.9) 10/15 44 ( 6.2 ) 03/16 49 (6.6) 04/18 46 (6.4)
cholesterol --nov 2011 4.3 june 2012 4.4 June 2013 4.1 Feb 2014 4.1 dec 14 4.5 oct 15 4.4
Dafne grad. necrobiosis lipoidica on legs
laser treatment on both eyes 2002 and 2012, injections left eye 3 , wearing Noctura mask since oct 2014