Author Topic: Statins  (Read 1226 times)

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Offline Liam

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Statins
« on: 26 January 2016, 01:36:37 PM »
Was watching a video about stress which talked about statins as an example. Seems 300 people need to take it for 1 person to have any benefit and that you are 15 times more likely to have a side effect than it helping.

https://www.youtube.com/watch?v=8jPQjjsBbIc

DX Type I 1994.    Novorapid Animas Vibe pump
HbA1c 3/10 10.2%, 7/10 8.1%, 12/10 7.5%.
2/11 7.8%, 8/11 8.6% 9/11 8.3%.
3/12 62 (7.8%). 10/12 67 (8.3%)
4/13 63 (7.9%) 6/13 59 (7.5%)
1/14 71 (8.6%) 7/14 59 (7.5%) 11/14 (6.7%)
3/15 56 (7.3%) 12/15 49 (6.6%)
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Offline Pattidevans

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Re: Statins
« Reply #1 on: 26 January 2016, 02:50:07 PM »
Oh what a surprise!  I will watch the video when I am home (am on work PC with no speakers at the moment)
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 Sept 2017.  45 (6.3) April 2018.


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Offline lozzark

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Re: Statins
« Reply #2 on: 26 January 2016, 04:27:06 PM »
It is unfortunate that this talk contains an error.  He says 300 people need to take a statin before 1 person has his cholesterol lowered.  What he should have said is "for one person to receive any benefit".  Statins are very effective at lowering cholesterol in practically everybody.  A corollary is that out of possibly 300 people who have their cholesterol lowered,  only one receives benefit.  299 people who have their cholesterol lowered receive no benefit - so how can anyone think cholesterol has anything to do with heart disease?  There is a possible answer for this effect. 1 in 500 people have Familial hypercholesterolemia, very high cholesterol cause by genetic factors: these people are undoubtedly helped.  1 in 300 is 0.33% and one in 500 is 0.2%.  The chances of being helped are really tiny.
T2 Dx 2000 Metformin Gliclazide HbA1c 53 BP 129/79 Cholesterol 5.4, HDL 1.16, LDL 2.9.

Offline Pattidevans

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Re: Statins
« Reply #3 on: 26 January 2016, 05:14:56 PM »
I don't know if he said that 300 would have their cholesterol lowered or what he said, cos my eyes had glazed over by that time!
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 Sept 2017.  45 (6.3) April 2018.


© 2015 Patti Evans

Offline Liam

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Re: Statins
« Reply #4 on: 26 January 2016, 07:05:48 PM »
I should have checked the time he said it so people could skip lol I thought he said what he should have but only listen to it once. Just thought it was interesting how many need to take it for just 1 to be helped.
DX Type I 1994.    Novorapid Animas Vibe pump
HbA1c 3/10 10.2%, 7/10 8.1%, 12/10 7.5%.
2/11 7.8%, 8/11 8.6% 9/11 8.3%.
3/12 62 (7.8%). 10/12 67 (8.3%)
4/13 63 (7.9%) 6/13 59 (7.5%)
1/14 71 (8.6%) 7/14 59 (7.5%) 11/14 (6.7%)
3/15 56 (7.3%) 12/15 49 (6.6%)
Ramipril: 10mg Quetiapine: 550mg Metformin: 2000mg

Offline DBolding

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Re: Statins
« Reply #5 on: 28 March 2016, 05:30:24 PM »
I am on statins, and my understanding is they may increase your life for a slight amount, but they could lower your risk of cardiac troubles by 30%? I so far have not had any side effects from them so will continue taking them until there is evidence they are doing more good than bad.

-Oh, and btw, Im not 100% clued up on them either, lol
Daniel

I may have diabetes... but diabetes does not have me!

Type: Havent got a clue!?

HbA1c - 7.4 March 2010 (diagnoses)
HbA1c - 7.5 May
HbA1c - 7.5 July
HbA1c - 6.1 October 2011
HbA1c-  5.5 July 2012

HbA1c- 15(140) September 2015
HbA1c- 12.4(112) Jan 2016
hbA1c- 7.5(59) April 2016

Offline Pattidevans

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Re: Statins
« Reply #6 on: 28 March 2016, 06:20:50 PM »
Quote
so will continue taking them until there is evidence they are doing more good than bad.
I don't think you will ever see evidence that they do more good than bad.  Even the drug companies that produced them are now changing their tune. 
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 Sept 2017.  45 (6.3) April 2018.


© 2015 Patti Evans

Offline sedge

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Re: Statins
« Reply #7 on: 28 March 2016, 09:58:36 PM »
Yes but actually Daniel - how high is YOUR risk (not the average diabetic bloke - I mean YOU specifically) for a CVD?

WELL controlled diabetics aren't in the same high-risk category as POORLY controlled ones.  So that lowers your risk anyway.

However at my age, if I had NEVER smoked and didn't have diabetes - according to the NHS Q-risk calculator I would still have about a 15% chance now, of a CVD within 10 years (when I'd be 76) which increases to 33.6% just for diabetes, and if you stick the smoking back in, increases to 44%,  I do not actually see how taking a statin could possibly reduce my real risk( - and the damage that I do know that I have already done to my arteries, since I actually already have intermittent claudication!) - by MORE than if I had never smoked a fag in my life. 

I therefore can only conclude - even if I wanted to believe it in the first place - that it's rubbish!
Jenny

T1 DX 1972, pumping Novorapid 24/05/11

HbA1c - 7/07 8.7, 1/08 7.8, 9/08 8.4, 3/09 7.3, 7/09 7.2, 12/09 7.3, 11/10 8.1, 2/11 8.6, 9/11 6.5 2/12 6.4  5/12 50/6.7  11/12 52/6.9  01/13 46/6.4  06/16 46/6.4  12/16 45/6.4

Offline DBolding

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Re: Statins
« Reply #8 on: 01 April 2016, 12:46:00 AM »
How would I find out my risk? I've started getting kidney pains and they are the only change hmmm lol
Daniel

I may have diabetes... but diabetes does not have me!

Type: Havent got a clue!?

HbA1c - 7.4 March 2010 (diagnoses)
HbA1c - 7.5 May
HbA1c - 7.5 July
HbA1c - 6.1 October 2011
HbA1c-  5.5 July 2012

HbA1c- 15(140) September 2015
HbA1c- 12.4(112) Jan 2016
hbA1c- 7.5(59) April 2016

Offline DBolding

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Re: Statins
« Reply #9 on: 01 April 2016, 12:50:04 AM »
Found something on the NHS

So I'm a bloke, over weight, smoke, diabetic and always stressed. Hmm basically think I should already be dead lol
Daniel

I may have diabetes... but diabetes does not have me!

Type: Havent got a clue!?

HbA1c - 7.4 March 2010 (diagnoses)
HbA1c - 7.5 May
HbA1c - 7.5 July
HbA1c - 6.1 October 2011
HbA1c-  5.5 July 2012

HbA1c- 15(140) September 2015
HbA1c- 12.4(112) Jan 2016
hbA1c- 7.5(59) April 2016

Offline Pattidevans

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Re: Statins
« Reply #10 on: 01 April 2016, 07:14:02 PM »
oops... well you ain't anywhere near as overweight as you were Daniel!  Have a read of this https://people.csail.mit.edu/seneff/why_statins_dont_really_work.html
My own total chol is 5.8 but the Endo is very happy with it.  Chol can be too low as well you know.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 Sept 2017.  45 (6.3) April 2018.


© 2015 Patti Evans

Offline DBolding

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Re: Statins
« Reply #11 on: 01 April 2016, 09:49:39 PM »
I'm not as over weight as I was but obviously still am which I work on daily lol. My total chol is high apparently. But I don't remember how high maybe 7 but after reading the article I cannot see any positive reason for taking a statin. Think I will do a little more reading and then decide where to go.

At the moment I have stopped both of them due to kidney pains as i can only think it was them.
Daniel

I may have diabetes... but diabetes does not have me!

Type: Havent got a clue!?

HbA1c - 7.4 March 2010 (diagnoses)
HbA1c - 7.5 May
HbA1c - 7.5 July
HbA1c - 6.1 October 2011
HbA1c-  5.5 July 2012

HbA1c- 15(140) September 2015
HbA1c- 12.4(112) Jan 2016
hbA1c- 7.5(59) April 2016

Offline Pattidevans

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Re: Statins
« Reply #12 on: 01 April 2016, 10:33:05 PM »
There's a thread here somewhere with loads of links to read up about Statins.  Will find it later.
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 Sept 2017.  45 (6.3) April 2018.


© 2015 Patti Evans

Offline Pattidevans

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Re: Statins
« Reply #13 on: 01 April 2016, 10:34:52 PM »
Patti


Type 1.  Mis-diagnosed T2 May 2003, finally had CPeptide test 15/7/11 and proper diagnosis 1/9/11.  Now pumping Apidra with Roche Spirit Combo pump. Hba1c 6.1 Sept 2017.  45 (6.3) April 2018.


© 2015 Patti Evans

Offline Moby

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Re: Statins
« Reply #14 on: 02 April 2016, 01:17:27 AM »
bw
Moby

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